Semysinthetic biflavonoid Morelloflavone-7,4',7 ″,3‴,4‴-penta-O-butanoyl is a more potent inhibitor of Proprotein Convertases Subtilisin/Kex PC1/3 than Kex2 and Furin
CONCLUSIONS: BF4 is a potent and selective inhibitor of PC1/3.GENERAL SIGNIFICANCE: BF4 is the best candidate for further clinical studies on inhibition of PC1/3.PMID:34560176 | DOI:10.1016/j.bbagen.2021.130016
Source: Biochimica et Biophysica Acta - Category: Biochemistry Authors: Aline Aparecida de Souza D ébora Martins de Andrade F ábio da Silva Siqueira Juliana Fortes Di Iorio Marcia Paranho Veloso Camila de Moraes Coelho Claudio Viegas Junior Vanessa Silva Gontijo Marcelo Henrique Dos Santos Maria Cec ília Zorél Meneghetti Source Type: research
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