Genome-wide analysis of thyroid function in Australian adolescents highlights SERPINA7 and NCOA3

Conclusion Our findings resolve former contention regarding heritability estimates of thyroid function traits and TPOAb positivity. GWAS and gene-based association analysis identified variants accounting for a component of this heritability.PMID:34524976 | DOI:10.1530/EJE-21-0614

Source: European Journal of Endocrinology - September 15, 2021 Category: Endocrinology Authors: James Nolan Purdey J Campbell Suzanne J Brown Gu Zhu Scott Gordon Ee Mun Lim John Joseph Simone Cross Vijay Panicker Sarah E Medland Phillip Melton Lawrence J Beilin Trevor A Mori Benjamin Mullin Craig Pennell Carol Wang Frank Dudbridge John P Walsh Nicho Source Type: research