LncRNA HCG11 promotes 5-FU resistance of colon cancer cells through reprogramming glucose metabolism by targeting the miR-144-3p-PDK4 axis

CONCLUSION: In summary, this study reveals critical roles and molecular mechanisms of the HCG11-mediated 5-FU resistance through modulating the miR-144-3p-PDK4-glucose metabolism pathway in CRC.PMID:34542064 | DOI:10.3233/CBM-210212

Source: Cancer Biomarkers - September 20, 2021 Category: Cancer & Oncology Authors: Zhi Cui Qi Wang Mu-Hong Deng Quan-Li Han Source Type: research