Serum cytokine/chemokine profiles predict hepatitis B reactivation in HBV/HCV co-infected subjects receiving direct-acting antiviral agents

CONCLUSION: Higher serum TNF-alpha at baseline and lower IFN-gamma at week 4 were associated with mild clinical reactivation of HBV in patients with HBV/HCV co-infection receiving DAAs. Combination of these cytokines reliably predicted HBV reactivation early.PMID:34538552 | DOI:10.1016/j.jfma.2021.09.002

Source: J Formos Med Assoc - September 20, 2021 Category: General Medicine Authors: Shang-Chin Huang Pin-Nan Cheng Chen-Hua Liu Hung-Chih Yang Tung-Hung Su Tai-Chung Tseng Pei-Jer Chen Jia-Horng Kao Chun-Jen Liu Source Type: research