Muscle Magnetic Resonance Imaging in Patients with LAMA2-Related Muscular Dystrophy

The LAMA2 gene encodes laminin α2, which is one of the three constituents of laminin-α2β1γ1 [1,2]. LAMA2 pathogenic variants cause a spectrum of rare autosomal recessive muscular dystrophy known as LAMA2-related muscular dystrophy (LAMA2-MD), classified into early-onset congenital muscular dystrophy type 1A (MDC1A) and late-o nset autosomal recessive limb-girdle muscular dystrophy-23 (LGMDR23) [3,4].

Source: Neuromuscular Disorders - September 23, 2021 Category: Neurology Authors: Dandan Tan, Lin Ge, Yanbin Fan, Cuijie Wei, Haipo Yang, Aijie Liu, Jiangxi Xiao, Hui Xiong, Ying Zhu Source Type: research