Prognostic factors and outcome of pineoblastoma: 10 years single-center experience

CONCLUSIONS: A multimodality approach is needed to treat this aggressive disease. Inadequate dose intensity affected our patients' outcome negatively. A more aggressive approach using high-dose chemotherapy or CSI may be required to improve infantile pineoblastoma's dismal outcome. Focal radiotherapy is not an efficacious treatment in infants due to its high-metastatic potential. Molecular typing should be considered to label patients who need a more intensified approach.PMID:34541625 | DOI:10.1186/s43046-021-00083-3
Source: J Egypt Natl Canc In... - Category: Cancer & Oncology Authors: Source Type: research