Regulatory role of Apelin-13-mediated PI3K/AKT signaling pathway in the glucose and lipid metabolism of mouse with gestational diabetes mellitus

CONCLUSION: Apelin-13, possibly by activating the PI3K/AKT pathway, could improve the glucose and lipid metabolism, reduce the damage caused by oxidative stress and inflammatory reaction, and protect the pancreas islet, thereby improving the pregnancy outcome of GDM mice.PMID:34521048 | DOI:10.1016/j.imbio.2021.152135
Source: Immunobiology - Category: Allergy & Immunology Authors: Source Type: research