Arrhythmia in Cardiomyopathy: Sex and Gender Differences

AbstractPurpose of ReviewThere is emerging evidence for important sex differences in cardiac arrhythmias. In this up-to-date review, we summarise the differences in incidence, aetiology, treatment and prevention of ventricular arrhythmias (VAs) and sudden cardiac death (SCD) in women versus men, in the context of ischaemic and nonischaemic cardiomyopathies.Recent FindingsThe incidence of ventricular tachyarrhythmia and SCD is significantly lower in women than in men with ischaemic cardiomyopathy, whereas sex differences in nonischaemic cardiomyopathy are less clear. Women who receive a primary prevention implantable cardioverter-defibrillator (ICD) are less likely to receive appropriate activations, compared to men; however, such findings are limited by under-representation of women.SummaryWomen with ischaemic cardiomyopathy have significantly lower incidence of VA and SCD compared to men and may not derive the same benefit from a primary prevention ICD. However, further clinical ICD studies are needed that ensure adequate female participation, in order to examine sex differences in outcomes in both ischaemic and nonischaemic cardiomyopathies.
Source: Current Heart Failure Reports - Category: Cardiology Source Type: research

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Source: Frontiers in cellular and infection microbiology - Category: Microbiology Source Type: research
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Source: Obstetrical and Gynecological Survey - Category: OBGYN Tags: CME ARTICLES Source Type: research
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Source: Heart Rhythm - Category: Cardiology Authors: Source Type: research
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Source: Canadian Journal of Veterinary Research - Category: Veterinary Research Authors: Source Type: research
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