The analysis of BDNF gene polymorphism haplotypes and impulsivity in methamphetamine abusers

An increasing number of evidence showed that genetic factors might contribute to drug abuse vulnerability. Data from genetic scans in humans suggest that brain-derived neurotrophic factor (BDNF), a member of the neurotrophic factor family, may be associated with substance abuse or dependence. To test the hypothesis that the BDNF gene polymorphism is involved in methamphetamine abuse, we compared three single nucleotide polymorphisms (SNPs, rs16917204, rs16917234, and rs2030324)of the BDNF gene in 200 methamphetamine abusers and 219 healthy individuals.

http://www.comppsychjournal.com/article/S0010-440X(15)00033-4/abstract?rss=yes

Source: Comprehensive Psychiatry - March 4, 2015 Category: Psychiatry Authors: Hang Su, Jingyan Tao, Jie Zhang, Ying Xie, Bin Han, Yuling Lu, Haiwei Sun, Youdan Wei, Yue Wang, Yu Zhang, Shengzhen Zou, Wenxiu Wu, Jiajia Zhang, Ke Xu, Xiangyang Zhang, Jincai He Source Type: research