Hepatocellular Carcinoma

CONCLUSIONS: The findings indicate that HCCs in noncirrhotic livers demonstrate a larger tumor size; have a more macrotrabecular histologic pattern; have fibrolamellar, macrotrabecular-massive, and clear cell subtypes; have a higher tumor grade and stage; have a higher rate of vascular invasion; and have more anaplastic tumor cells compared with cirrhotic livers. Further studies to explore different pathways that promote oncogenesis in noncirrhotic livers are needed to better understand the pathogenesis of HCC.PMID:34542582 | DOI:10.1093/ajcp/aqab125
Source: American Journal of Clinical Pathology - Category: Pathology Authors: Source Type: research