Anxiolytic- and antidepressant-like effects of new phenylpiperazine derivative LQFM005 and its hydroxylated metabolite in mice

In conclusion, oral administration of the newly synthesized phenylpiperazines produced anxiolytic- and antidepressant-like effects in behavioral tests, putatively in part through the activation of 5-HT1A receptors.PMID:34536431 | DOI:10.1016/j.bbr.2021.113582

Source: Behavioural Brain Research - September 18, 2021 Category: Neurology Authors: Lorrane Kelle da Silva Moreira Rafaela Ribeiro Silva Dayane Moreira da Silva Mirella Andrade Silva Mendes Adriane Ferreira de Brito Fl ávio Souza de Carvalho Germ án Sanz Marcella Ferreira Rodrigues Artur Christian Garcia da Silva Douglas Vieira Thomaz Source Type: research