Cognitive Outcome After Deep Brain Stimulation for Refractory Obsessive –Compulsive Disorder: A Systematic Review

ConclusionAlthough individual studies generally do not report cognitive deterioration after DBS for OCD, the variability of study designs and the multitude of cognitive measures used, precluded a meta-analysis to confirm its safety, and recognition of a cognitive pattern through which the efficacy of DBS for OCD might be explained. In future, prospective studies should preferably include a standardized neuropsychological assessment battery specifically addressing executive functioning and have a longer-term follow-up in order to demonstrate the cognitive safety of the procedure. Such prospective and more uniform data collection may also contribute to our understanding of the working mechanisms of DBS in OCD.

Source: Neuromodulation: Technology at the Neural Interface - September 21, 2021 Category: Biotechnology Authors: Tim A. M. Bouwens van der Vlis, Annelien Duits, M égan M. G. H. Veerdonk, Anne E. P. Mulders, Koen R. J. Schruers, Yasin Temel, Linda Ackermans, Albert F. G. Leentjens Tags: Review Article Source Type: research