NEP1-40-overexpressing neural stem cells enhance axon regeneration by inhibiting Nogo-A/NgR1 signaling pathway

CONCLUSION: NEP1-40 overexpression enhanced the ability of NSCs differentiation into neurons and promoted axon regeneration by inhibiting the Nogo-A/NgR1 signaling pathway. This study provides an alternative gene modified transplantation NSCs for the SCI treatment.PMID:34544340 | DOI:10.2174/1567202618666210920115716

Source: Current Neurovascular Research - September 21, 2021 Category: Neurology Authors: Bi Zhang Dalin Wang Xusheng Li Shengsen Yang Haifeng Yuan Source Type: research