Cancers, Vol. 13, Pages 4725: Prognostic Role of Preoperative Sarcopenia Evaluation of Cervical Muscles with Long-Term Outcomes of Patients with Oral Squamous Cell Carcinoma

In this study, we investigated whether preoperative lumbar (L3) skeletal muscle mass and adiposity in OSCC patients were associated with cervical (C3) skeletal muscle mass and adiposity from CT measurements. We also investigated whether skeletal muscle mass and adiposity in the C3 muscles were associated with survival rates in patients with OSCC. We demonstrated that both the quality and quantity of muscle between the C3 and L3 levels were positively correlated with each other. We also demonstrated that the survival rates in patients with low sternocleidomastoid muscle mass index, high processus spinosus muscle-intramuscular adipose tissue content, and the combination of both were significantly lower than those in the controls. These results suggest that the assessment of sarcopenia from multiple neck muscles by preoperative CT measurements may be useful in predicting the prognosis of patients with OSCC.

Source: Cancers - September 21, 2021 Category: Cancer & Oncology Authors: Takuya Yoshimura Hajime Suzuki Hirotaka Takayama Shotaro Higashi Yuka Hirano Masahiro Tezuka Takayuki Ishida Kiyohide Ishihata Marie Amitani Haruka Amitani Yasuhiro Nishi Yasunori Nakamura Yasushi Imamura Etsuro Nozoe Norifumi Nakamura Tags: Article Source Type: research