Response to sertraline is associated with reduction in anxiety-potentiated startle in premenstrual dysphoric disorder

ConclusionThese data demonstrate elevated psychophysiologic arousal in the luteal phase among some women with PMDD, suggesting impaired ability to modulate arousal reactivity. Specifically, alterations in APS suggest potential GABA-A-R changes across the menstrual cycle and in response to sertraline among treatment responders.
Source: Psychopharmacology - Category: Psychiatry Source Type: research