Anisakis simplex: Immunomodulatory effects of larval antigens on the activation of Toll like Receptors

CONCLUSION: Our findings confirm not only that the host genetic basis plays a role in the development of a Th2/Th1/Treg response, but also it states A. simplex larval antigens present specific mechanisms to modify the innate response of the host. As allergies share common pathways with the immune response against this particular helminth, our results provide a better understanding into the specific mechanisms of A. simplex allergy related diseases.PMID:34537480 | DOI:10.1016/j.intimp.2021.108120
Source: International Immunopharmacology - Category: Allergy & Immunology Authors: Source Type: research