6-Gingerol protects against cerebral ischemia/reperfusion injury by inhibiting NLRP3 inflammasome and apoptosis via TRPV1 / FAF1 complex dissociation-mediated autophagy
CONCLUSION: In brief, 6-Gingerol exerts antiapoptotic and anti-inflammatory effects via TRPV1/FAF1 complex dissociation-mediated autophagy during cerebral I/R injury. Therefore, 6-Gingerol may be an effective drug for the treatment of I/R injury.PMID:34537481 | DOI:10.1016/j.intimp.2021.108146
Source: International Immunopharmacology - Category: Allergy & Immunology Authors: Jing Luo Jialei Chen Changhong Yang Junyi Tan Jing Zhao Ning Jiang Yong Zhao Source Type: research