Sex-specific effect of prenatal alcohol exposure on N-Methyl-D-Aspartate Receptor function in orbitofrontal cortex pyramidal neurons of mice

CONCLUSIONS: These findings suggest that low-to-moderate PAE modulates NMDAR function in pyramidal neurons in a sex specific manner, although we did not find evidence that this is mediated by dysfunction of synaptic GluN2B subunit-containing NMDARs.PMID:34523139 | DOI:10.1111/acer.14697
Source: Alcoholism, Clinical and Experimental Research - Category: Addiction Authors: Source Type: research