Extracellular matrix protein N-glycosylation mediates immune self-tolerance in Drosophila melanogaster [Genetics]

In order to respond to infection, hosts must distinguish pathogens from their own tissues. This allows for the precise targeting of immune responses against pathogens and also ensures self-tolerance, the ability of the host to protect self tissues from immune damage. One way to maintain self-tolerance is to evolve a...

Source: Proceedings of the National Academy of Sciences - September 20, 2021 Category: Science Authors: Nathan T. Mortimer, Mary L. Fischer, Ashley L. Waring, Pooja KR, Balint Z. Kacsoh, Susanna E. Brantley, Erin S. Keebaugh, Joshua Hill, Chris Lark, Julia Martin, Pravleen Bains, Jonathan Lee, Alysia D. Vrailas-Mortimer, Todd A. Schlenke Tags: Genetics Biological Sciences Source Type: research