Therapeutic effects, immunogenicity and cytotoxicity of a cell penetrating peptide-peptide nucleic acid conjugate against cagA of Helicobacter pylori in cell culture and animal model
CONCLUSION: These results suggest the effectiveness of CPP-PNA in targeting CagA for various research and therapeutic purposes, offering a potential antisense therapy against H. pylori infections.PMID:34540175 | PMC:PMC8416595 | DOI:10.18502/ijm.v13i3.6399
Conditions: Gastric Cancer; Metastasis Interventions: Drug: Apatinib Mesylate; Drug: Camrelizumab Sponsor: Fudan University Recruiting
Conditions: B Cell Leukemia; Lymphoma Intervention: Genetic: SNP analysis of the DNA Sponsor: Asfendiyarov Kazakh National Medical University Not yet recruiting
Condition: Metastatic Pancreatic Ductal Adenocarcinoma Intervention: Drug: Onivyde® + 5-FULV Sponsors: University Hospital, Antwerp; Universitair Ziekenhuis Brussel; AZ Nikolaas; General Hospital Groeninge; University Hospital St Luc, Brussels; ASZ Aalst; Erasme University Hospital; Centre Hospitalier Universitaire de Liège Not yet recruiting
Condition: Non-Hodgkin's Lymphoma Intervention: Drug: [ 18F]F-AraG PET Sponsors: Stanford University; CellSight Technologies, Inc. Recruiting
Staphylococcus aureus is an important pathogen causing a wide variety of diseases such as skin infections, food poisoning, pneumonia and septicemia in humans and animals. Among the bacterial agents of food poisoning, S. aureus is the most common agent worldwide. The aim of this study was to assess prevalence of SEA, SEB enterotoxin producing S. aureus isolated from foodborne outbreaks in Ira...
OBJECTIVE: To investigate the quality of life (QOL) of injured motorcyclists and associated factors in a period of three months after the accident. METHODS: In the present study, we were included 190 injured motorcyclists who admitted to two referr...
PURPOSE: Traumatic brain injury (TBI) is one of the major public health concerns worldwide. Developing a TBI registry could facilitate characterizing TBI, monitoring the quality of care, and quantifying the burden of TBI by collecting comparable and standa...