Assessing disease activity using the pediatric Crohn's disease activity index: Can we use subjective or objective parameters alone?

CONCLUSION: Although subjective items on the PCDAI change the most over time, the full PCDAI or a smaller composite of items including a combination of subjective and objective components classifies disease activity better than a subgroup of either subjective or objective items alone. Reliance on subjective or objective items as stand-alone proxies for disease activity measurement could result in misclassification of disease state.PMID:34497438 | PMC:PMC8384732 | DOI:10.3748/wjg.v27.i30.5100

Source: World Journal of Gastroenterology : WJG - September 9, 2021 Category: Gastroenterology Authors: Amy Grant Trudy Lerer Anne M Griffiths J S Hyams Anthony Otley Source Type: research