Transcriptome-wide analysis of intracranial artery in patients with moyamoya disease showing upregulation of immune response, and downregulation of oxidative phosphorylation and DNA repair

CONCLUSIONS: Transcriptome-wide analysis showed upregulation of genes for immune responses and downregulation of genes for DNA repair and oxidative phosphorylation within the intracranial artery of patients with MMD. These findings may represent clues to the pathophysiology of MMD.PMID:34469870 | DOI:10.3171/2021.6.FOCUS20870

Source: Neurosurgical Focus - September 1, 2021 Category: Neurosurgery Authors: Fumiaki Kanamori Kinya Yokoyama Akinobu Ota Kazuhiro Yoshikawa Sivasundaram Karnan Mikio Maruwaka Kenzo Shimizu Shinji Ota Kenji Uda Yoshio Araki Sho Okamoto Satoshi Maesawa Toshihiko Wakabayashi Atsushi Natsume Source Type: research