Cardiovascular Endurance Modifies the Link between Subjective Sleep Quality and Entorhinal Cortex Thickness in Younger Adults

Conclusions Higher cardiovascular endurance may mitigate the relationship between poorer subjective sleep quality and lower EC thickness. Future longitudinal studies should examine the interactive effects of sleep and fitness on brain health among older and more vulnerable populations.
Source: Medicine and Science in Sports and Exercise - Category: Sports Medicine Tags: APPLIED SCIENCES Source Type: research

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Mol Med. 2021 Sep 16;27(1):111. doi: 10.1186/s10020-021-00327-x.ABSTRACTParkinson's disease (PD) commences several years before the onset of motor features. Pathophysiological understanding of the pre-clinical or early prodromal stages of PD are essential for the development of new therapeutic strategies. Two categories of patients are ideal to study the early disease stages. Idiopathic rapid eye movement sleep behavior disorder (iRBD) represents a well-known prodromal stage of PD in which pathology is presumed to have reached the lower brainstem. The majority of patients with iRBD will develop manifest PD within years to ...
Source: Molecular Medicine - Category: Molecular Biology Authors: Source Type: research
Disrupted sleep and circadian rhythms are linked with substance abuse risk. Human studies that investigate relationships between sleep, circadian rhythm, and substance use reward generally rely on indirect means to infer dopaminergic function, such as functional magnetic resonance imaging. In this issue of the JCI, Zhang and colleagues used positron emission tomography (PET) to image striatal dopamine D1 (D1R) and D2/3 receptor (D/3R) availability in healthy adults. The authors assessed rest-activity rhythms, then conducted PET scans using radioligand antagonists selective for D1 receptors or D2/D3 receptors to measure D1R...
Source: Journal of Clinical Investigation - Category: Biomedical Science Authors: Source Type: research
Paediatr Anaesth. 2021 Sep 3. doi: 10.1111/pan.14290. Online ahead of print.ABSTRACTBACKGROUND: Dexmedetomidine is utilized as a sedative agent for drug induced sleep cine magnetic resonance imaging studies due to its ability to mimic natural sleep and lack of respiratory depressant effects. The outcomes of dexmedetomidine sedation such as respiratory complications and unplanned admissions in obstructive sleep apnea patients undergoing these studies are currently unknown.AIM: To describe the outcomes of dexmedetomidine sedation for outpatient drug induced sleep magnetic resonance imaging in pediatric patients with obstruct...
Source: Paediatric Anaesthesia - Category: Anesthesiology Authors: Source Type: research
CONCLUSIONS: Our novel imaging technique demonstrated reliable quantification of upper airway FDG avidity. This technology has implications for future work exploring local airway inflammation in individuals with OSA and exposure to pollutants. It may also serve as an assessment tool for response to OSA therapies.PMID:34448065 | DOI:10.1007/s11325-021-02480-3
Source: Sleep and Breathing - Category: Sleep Medicine Authors: Source Type: research
AbstractNeuroimaging findings suggest that the amygdala plays a primary role in both the psychopathology of posttraumatic stress disorder (PTSD) and poor sleep quality, which are common in trauma survivors. However, the neural mechanisms of these two problems in trauma survivors associated with amygdala remain unclear. In the current study, we aimed to explore the role of functional connectivity of amygdala subregions in both PTSD symptoms and poor sleep quality. A total of 94 trauma-exposed subjects were scanned on a 3T MR system using resting-state functional magnetic resonance imaging. Both Pittsburgh Sleep Quality Inde...
Source: European Archives of Psychiatry and Clinical Neuroscience - Category: Neuroscience Source Type: research
Researchers at King’s College London developed a virtual reality system that is intended to distract and calm patients who find MRI scans challenging, including children and other vulnerable individuals. The patient wears a specialized VR heads...
Source: Medgadget - Category: Medical Devices Authors: Tags: Materials Radiology Source Type: blogs
CONCLUSION: These findings highlight the important role of prefrontal cortex function during emotion regulation in the associations between stress, sleep disturbance and depressive symptoms. Increasing lateral prefrontal cortex recruitment when regulating the emotional response to negative life events may be critical for the prevention and intervention of depression as well as sleep problems.PMID:34254527 | DOI:10.1177/00048674211025729
Source: The Australian and New Zealand Journal of Psychiatry - Category: Psychiatry Authors: Source Type: research
This study aims to provide scientific evidence for the mechanism of acupuncture in treating CID with GI disorder using multimodal MRI imaging data on brain structure, function, and metabolism.Trial registrationChinese Clinical Trial Registry, ChiCTR1800017092  (URL:http://www.chictr.org.cn/showproj.aspx?proj=27173). Registered on July 11, 2018.
Source: Trials - Category: Research Source Type: clinical trials
Conclusion: MDD patients with GI symptoms showed a greater severity of symptoms than MDD patients without GI symptoms, particularly in terms of anxiety/somatization, weight loss, and sleep disturbances. Increased activity in the default-mode network might be associated with GI symptoms in MDD patients.
Source: Frontiers in Psychiatry - Category: Psychiatry Source Type: research
Journal of Clinical Sleep Medicine, Ahead of Print.
Source: Journal of Clinical Sleep Medicine : JCSM - Category: Sleep Medicine Authors: Source Type: research
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