Antiarrhythmic Agents: a Review and Comment on Relevance in the Current Era —Part 2

AbstractPurpose of reviewThere is apprehension and a general lack of familiarity with regards to using the “membrane-active” antiarrhythmic agents among internists and even general cardiologists.Recent findingsThis hesitancy regarding use of these agents may be related to their relative infrequent use, complicated mechanisms of actions, and real or perceived risks involved with their use. For example, the fact that dofetilide requires prescription only by certified electrophysiologists and hospitalization for initiation creates a mystique about its use.SummaryThis review paper will attempt to lay out the general pharmacology of the commonly used drugs and discuss their relevance and safe use in current clinical medicine.
Source: Current Treatment Options in Cardiovascular Medicine - Category: Cardiology Source Type: research