Rhinocerebral Mucormycosis as a Sequelae of COVID-19 Treatment: A Case Report & Literature Review

A large volume of reports detailing a marked increase in Mucormycosis infections in India has filtered its way into world news articles. These patients frequently have 2 risk factors: recent treatment of COVID-19 with high dose steroids, and uncontrolled diabetes. Recently, at the University of Tennessee Medical Center in Knoxville, we successfully treated an uncontrolled diabetic patient with rhinocerebral Mucormycosis as a sequela of his COVID-19 treatment.
Source: Journal of Oral and Maxillofacial Surgery - Category: ENT & OMF Authors: Tags: Pathology Source Type: research

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Review (186 studies representing 210,447 deaths among 1,304,587 patients with COVID-19) suggests diabetes (1.54 fold), hypertension (1.42), obesity (1.45) and smoking (1.28) are associated with higher COVID-19 mortality, contributing to nearly 30% of COVID-19 deaths.
Source: Current Awareness Service for Health (CASH) - Category: Consumer Health News Source Type: news
This study aimed to detect patients ’ characteristics who suffered severe and critical COVID-19 pneumonia admitted to the post-acute COVID-19 rehabilitation clinic in Ankara City Hospital, Physical Medicine and Rehabilitation Hospital and to share our experiences and outcomes of rehabilitation programmes applied. This study was desi gned as a single-centre, retrospective, observational study. Severe and critical COVID-19 patients, admitted to the post-acute COVID-19 rehabilitation clinic, were included in patient-based rehabilitation programmes, targeting neuromuscular and respiratory recovery. Functional status, oxy...
Source: Rheumatology International - Category: Rheumatology Source Type: research
Conclusions: The COVID-19 epidemic might increase the ODT of patients with TIA/mild stroke.
Source: Frontiers in Neurology - Category: Neurology Source Type: research
Conclusion: This work is a pilot study with preliminary results. To date, relatively few projects and trials in diabetic patients have been run within the “telemedicine 2.0” setting, particularly using AI, ICT and the Web 2.0 in the era of COVID-19 disease.
Source: Frontiers in Physiology - Category: Physiology Source Type: research
COVID-19 vaccines are already authorized for children ages 12 and older, and the shots now have the support of a U.S. Food and Drug Administration (FDA) expert panel for younger children ages 5 to 11. In a 17 to 0 vote, with one abstention, the committee recommended the COVID-19 vaccine made by Pfizer-BioNTech for the youngest group yet to potentially get immunized against the disease in the US. The committee recommended a two-dose regimen at one-third the dosage approved for adults. The FDA now takes the committee’s advice into consideration before making a final recommendation. If the agency decides to recommend th...
Source: TIME: Health - Category: Consumer Health News Authors: Tags: Uncategorized COVID-19 Source Type: news
Expert Rev Clin Immunol. 2021 Oct 26. doi: 10.1080/1744666X.2021.1997592. Online ahead of print.ABSTRACTINTRODUCTION: In daily practice management of psoriasis, evaluation of risk factors for infections is having a growing influence. Indeed, in psoriatic patients, risk of infections may be due to psoriasis itself, immunomodulatory therapy and comorbidities that may increase this risk and patient hospitalization.AREAS COVERED: Given the greater understanding of psoriasis pathogenesis and the increasing number of treatment options, it is particularly important to customize therapy according to each, single patient; psoriasis...
Source: Expert Review of Clinical Immunology - Category: Allergy & Immunology Authors: Source Type: research
Curr Issues Mol Biol. 2021 Sep 22;43(3):1212-1225. doi: 10.3390/cimb43030086.ABSTRACTThe coronavirus SARS-CoV-2 is the cause of the ongoing COVID-19 pandemic. Most SARS-CoV-2 infections are mild or even asymptomatic. However, a small fraction of infected individuals develops severe, life-threatening disease, which is caused by an uncontrolled immune response resulting in hyperinflammation. However, the factors predisposing individuals to severe disease remain poorly understood. Here, we show that levels of CD47, which is known to mediate immune escape in cancer and virus-infected cells, are elevated in SARS-CoV-2-infected ...
Source: Current Issues in Molecular Biology - Category: Molecular Biology Authors: Source Type: research
Diabetes Metab. 2021 Oct 23:101297. doi: 10.1016/j.diabet.2021.101297. Online ahead of print.NO ABSTRACTPMID:34699977 | PMC:PMC8536836 | DOI:10.1016/j.diabet.2021.101297
Source: Diabetes and Metabolism - Category: Endocrinology Authors: Source Type: research
A few weeks ago, we kickstarted a new series of articles contemplating the moves of pharmaceutical heavyweights in the digital health arena. The first batch of companies, Johnson &Johnson, Pfizer, Bayer and Novartis, seem to have some interest in remote healthcare solutions and DTx.  In this second article, we will explore which trends pharma giants Merck, GlaxoSmithKline, AbbVie, Sanofi and Bristol Myers Squibb are eyeing. Merck: big tech-friendly A big pharma company itself, Germany’s Merck hasn’t shied from teaming up with big tech companies in recent years as it aims to make a lasting ...
Source: The Medical Futurist - Category: Information Technology Authors: Tags: Artificial Intelligence in Medicine Biotechnology Future of Medicine Future of Pharma Health Sensors & Trackers Personalized Medicine Portable Medical Diagnostics Security & Privacy pharmaceutics 23andme philips big pharma Merck Source Type: blogs
AbstractSevere acute respiratory syndrome coronavirus  2 (SARS-CoV-2) causes coronavirus disease 2019 (COVID-19). The latter is a pandemic that has the potential of developing into a severe illness manifesting as systemic inflammatory response syndrome, acute respiratory distress syndrome, multi-organ involvement and shock. In addition, advanced age a nd male sex and certain underlying health conditions, like type 2 diabetes mellitus (T2DM), predispose to a higher risk of greater COVID-19 severity and mortality. This calls for an urgent identification of antidiabetic agents associated with more favourable COVID-1...
Source: Diabetes Therapy - Category: Endocrinology Source Type: research
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