Dmd/bmd - genetics
Although intellectual disability was included in the first description of Duchenne muscular dystrophy (DMD), the cognitive and neurodevelopmental (ND) components of DMD and Becker muscular dystrophy (BMD) remain overshadowed by their motor, cardiac, and pulmonary manifestations. To assess the ND comorbidity burden in dystrophinopathy patients at Le Bonheur Children's Hospital neuromuscular clinic, abstraction of the electronic medical record was performed for 46 patients. Diagnoses of ADHD, epilepsy, autism spectrum, obsessive compulsive, oppositional defiant, mood, anxiety, and sleep disorders, along with discussion of any cognitive difficulties, shyness, or other maladaptive behaviors, were recorded for each patient.
People with different types of disabilities tested their skills and technologies on a zero-gravity research flight with the goal of proving that they can safely go to space.
HIGHLANDS RANCH, Colo., Oct. 19, 2021 /PRNewswire/ -- Vivos Therapeutics, Inc. ( " Vivos " or " the Company " ) (NASDAQ: VVOS), a medical technology company focused on developing and commercializing innovative diagnostic and treatment modalities for patients suffering from mild to moderate obstructive sleep apnea (OSA) and snoring, and Candid Care Co. ( " Candid " ), a digital platform for oral healthcare, today announced a new collaboration that will seek to provide patients with a comprehensive, whole-mouth solution to diagnose and treat OSA in adult patients and provide ...
This study aims to adopt a strength-based model that investigates the mediating role of parental playfulness in the association between parent–child relationship and parental competence. This study is a quantitative study that adopts a correlational research design. The mediation analysis explores the role of parental playfulness as a mediator in the association between parent–child relationship and parental competence. The sample consisted of 120 parents of children diagnosed with ASD from India, selected using a purposive sampling technique. The mediation analysis results indicate that playfulness among...
Time to confirmed disability worsening was longer in patients who received dimethyl fumarate, compared with those who received teriflunomide, in an analysis of real-world data.Medscape Medical News
Dr. Laura Esserman answers the door of her bright yellow Victorian home in San Francisco’s Ashbury neighborhood with a phone at her ear. She’s wrapping up one of several meetings that day with her research team at University of California, San Francisco, where she heads the Carol Franc Buck Breast Care Center. She motions me in and reseats herself at a makeshift home office desk in her living room, sandwiched between a grand piano and set of enormous windows overlooking her front yard’s flower garden. It’s her remote base of operations when she’s not seeing patients or operating at the hospita...
Breast imaging can be associated with substantial anxiety due to the impact of abnormal mammography on distress and perceptions of risk for breast cancer. We sought to determine the level of anxiety after notification of abnormal mammography and need for follow up at a cancer institute and whether or not further distress was provoked by the visit to the ‘cancer institute’ for follow up.
There is an association between obesity, Obstructive Sleep Apnea, and Upper Airway Volume (UAWV). Measurement of the Tongue Length (TL) and Height (TH) recently emerged as a non-invasive method of evaluation of the UAWV and tinge architecture. We hypothesized that bariatric surgery-induced rapid weight loss determines an increase of Upper Respiratory Airway volume.
The pulmonary artery diameter (PAD) and its ratio with the ascending aorta diameter (PAD/AoD ratio) are predictors of pulmonary hypertension (PH). Severe obesity increases the risk of PH due to its association with left ventricular dysfunction and obstructive sleep apnea. The aim of this study was to identify changes in the PAD and PA/AoD ratio after bariatric surgery (BaS) using chest computed tomography (CT).
We report the validation of these SSI against conventional scoring systems and mortality in a multi-institutional trauma registry in Cameroon.
Trauma and catastrophes seen by surgeons, medics and first responders puts them at high risk for developing depression, anxiety, PTSD and associated suicide. Both exaggerated/high and blunted/low stress reactivity (HPA) axis has been shown to correlate with poor mental health, along with a pro-inflammatory state. We hypothesis that cortisol reactivity and cytokine levels correlate with mental disorder risk and traumatic life experiences.