Dmd - brain

A proportion of patients with Duchenne muscular dystrophy (DMD) have behavioural and cognitive deficits. Magnetic resonance imaging (MRI) has demonstrated reduced grey matter volume, altered white matter structural integrity and reduced perfusion compared to age-matched controls. Here we report the first results of a longitudinal study of brain structure in adolescents with DMD compared controls. 28 DMD and 20 control participants were scanned, with a 2- to 4-year time-window. 3D T1-weighted scans were acquired at 3 Tesla.

Source: Neuromuscular Disorders - September 19, 2021 Category: Neurology Authors: N. Doorenweerd, M. Hoegen, E. Broek, K. Hollingsworth, C. Marini-Bettolo, J. Hendriksen, E. Niks, V. Straub, H. Kan Source Type: research