New insights into cellular or muscle function

Skeletal muscle contains multiple cell types that work together to maintain tissue homeostasis. Among these, satellite cells (SC) and fibroadipogenic precursor cells (FAPs) are the two main stem cell pools. Studies of these cells using animal models have shown the importance of interactions between these cells in repair of healthy muscle, and degeneration of dystrophic muscle. Due to the unavailability of fresh patient muscle biopsies, similar analysis of interactions between human FAPs and SCs is limited especially amongst the muscular dystrophy patients.

Source: Neuromuscular Disorders - September 19, 2021 Category: Neurology Authors: X. Su árez-Calvet, E. Fernández-Simón, P. Piñol-Jurado, J. Alonso-Pérez, A. Carrasco-Rozas, C. Lleixà, S. López-Fernández, G. Pons, L. Soria, A. Bigot, I. Illa, E. Gallardo, J. Jaiswal, J. Díaz-Manera Source Type: research