Virtual Exercise Rehabilitation Treatment Program for Post Exacerbation of Chronic Obstructive Pulmonary Disease

Condition:   COPD Intervention:   Other: Virtual rehabilitation Sponsors:   St. Joseph's Healthcare Hamilton;   Boeringer Ingelheim Not yet recruiting
Source: ClinicalTrials.gov - Category: Research Source Type: clinical trials

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SPRING HOUSE, PENNSYLVANIA, October 25, 2021 – The Janssen Pharmaceutical Companies of Johnson &Johnson today announced data from two new analyses of STELARA® (ustekinumab) for the treatment of adults with moderately to severely active Crohn’s disease (CD) and ulcerative colitis (UC).1,2 In a modelled analysisa focused on treatment sequencing using data from randomized controlled trials, network meta-analysis and literature, results showed patient time spent in clinical remission or response was highest when STELARA was used as a first-line advanced therapy for bio-naïve patients with moderately to...
Source: Johnson and Johnson - Category: Pharmaceuticals Tags: Innovation Source Type: news
Conditions:   COPD;   ILD Intervention:   Diagnostic Test: single high-fidelity expiratory CO2 analysis Sponsor:   Medical University of Graz Recruiting
Source: ClinicalTrials.gov - Category: Research Source Type: clinical trials
We thank Elsharkawi et  al. for their comments on our paper, which rebuts the premise of abdominal aortic aneurysm (AAA) rupture risk due to pulmonary function testing (PFT).1 As a parallel, rupture rates, even when awaiting treatment of large/complex AAA by fenestrated/branched endovascular aneurysm repair, are low.2 Wh ile they indicate slightly different scenarios, we would be interested to know if these patients had PFTs or not, given that they were referred with concomitant lung pathology, and also such patients represent a group recognised as often having a past/recent history of smoking,3 with varying degrees o...
Source: European Journal of Vascular and Endovascular Surgery - Category: Surgery Authors: Tags: Letter to the Editor Source Type: research
​​ NHLBI TOPMed: SubPopulations and InteRmediate Outcome Measures In COPD Study (SPIROMICS)  (study page |release notes)
Source: dbGaP, the database of Genotypes and Phenotypes - Category: Genetics & Stem Cells Tags: StudyRelease Source Type: research
AbstractPurposeFound in inflammatory zone 2 (FIZZ2) is associated with lung inflammation. The aim of the study was to investigate the expression and utility of FIZZ2 as a marker for chronic obstructive pulmonary disease (COPD).MethodsImmunohistochemistry was used to detect the expression of FIZZ2 in COPD. The serum concentration of FIZZ2 was measured by enzyme-linked immunosorbent assay and the episodes of acute exacerbations of COPD (AECOPD) in the following year were recorded.ResultsFIZZ2 expression was elevated in bronchial epithelial cells (0.217  ± 0.021 vs 0.099 ± 0.010,p 
Source: Lung - Category: Respiratory Medicine Source Type: research
Beta-blocker therapies for cardiovascular comorbidities are often withheld in patients with chronic obstructive pulmonary disease (COPD) due to potential adverse effects on airway obstruction. We carried out a...
Source: Respiratory Research - Category: Respiratory Medicine Authors: Tags: Research Source Type: research
This study aimed to elucidate...
Source: Respiratory Research - Category: Respiratory Medicine Authors: Tags: Research Source Type: research
AbstractPurposeFound in inflammatory zone 2 (FIZZ2) is associated with lung inflammation. The aim of the study was to investigate the expression and utility of FIZZ2 as a marker for chronic obstructive pulmonary disease (COPD).MethodsImmunohistochemistry was used to detect the expression of FIZZ2 in COPD. The serum concentration of FIZZ2 was measured by enzyme-linked immunosorbent assay and the episodes of acute exacerbations of COPD (AECOPD) in the following year were recorded.ResultsFIZZ2 expression was elevated in bronchial epithelial cells (0.217  ± 0.021 vs 0.099 ± 0.010,p 
Source: Lung - Category: Respiratory Medicine Source Type: research
by Charlie M. Carpenter, Weiming Zhang, Lucas Gillenwater, Cameron Severn, Tusharkanti Ghosh, Russell Bowler, Katerina Kechris, Debashis Ghosh High-throughput data such as metabolomics, genomics, transcriptomics, and proteomics have become familiar data types within the “-omics” family. For this work, we focus on subsets that interact with one another and represent these “pathways” as graphs. Observed pathways often have disjoint components, i.e., nodes or sets of nodes (metabolites, etc.) not connected to any other within the pathway, which notably lessens testing power. In this paper we propose t...
Source: PLoS Computational Biology - Category: Biology Authors: Source Type: research
Among patients hospitalized for chronic obstructive pulmonary disease (COPD), the risk for discharge to another facility or for death in hospital was significantly greater than for patients without sepsis.Medscape Medical News
Source: Medscape Medical News Headlines - Category: Consumer Health News Tags: Pulmonary Medicine News Source Type: news
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