Statin Cholesterol Drugs May Help Fight Ulcerative Colitis

Title: Statin Cholesterol Drugs May Help Fight Ulcerative ColitisCategory: Health NewsCreated: 9/16/2021 12:00:00 AMLast Editorial Review: 9/17/2021 12:00:00 AM
Source: MedicineNet Digestion General - Category: Nutrition Source Type: news

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STATINS are a group of medicines that can help lower the level of cholesterol in the blood. Satins can also be taken to prevent heart disease, including heart attacks and strokes. Now, a new study has found that the cheap pills may also help treat ulcerative colitis.
Source: Daily Express - Health - Category: Consumer Health News Source Type: news
Stanford University researchers have found that atrorvastatin - sold under the name Lipitor for just 54p a pill - slashes the risk of being hospitalised with the painful condition by half.
Source: the Mail online | Health - Category: Consumer Health News Source Type: news
Statins, the cholesterol-lowering drugs, may also help treat the symptoms of ulcerative colitis, a study published by the Journal of the American Medical Informatics Association found.
Source: Health News - UPI.com - Category: Consumer Health News Source Type: news
Psyllium is a natural, predominantly soluble isolated fiber that forms a gel when hydrated. The psyllium gel is not fermented and transits the entire gastrointestinal tract intact. In the small intestine, the psyllium gel increases chyme viscosity, which slows the degradation and absorption of nutrients, which significantly improves fasting blood glucose and hemoglobin A1c levels in individuals with metabolic syndrome and type 2 diabetes mellitus (eg, −37 mg/dL). This delay in nutrient absorption prolongs satiety/delays hunger, leading to decreased energy intake and weight loss in overweight and obese patients. In th...
Source: Nutrition Today - Category: Nutrition Tags: Nutrition Science Source Type: research
Condition:   Ulcerative Colitis Intervention:   Drug: Rosuvastatin 10mg Sponsors:   Universitaire Ziekenhuizen Leuven;   Vlaams Instituut Biotechnologie (VIB) Recruiting
Source: ClinicalTrials.gov - Category: Research Source Type: clinical trials
Source: Gastroenterology - Category: Gastroenterology Authors: Tags: AGA Abstracts Source Type: research
This study may have important implications for preventing cell senescence and aging-induced tendinopathy, as well as for the selection of novel therapeutic targets of chronic tendon diseases. Our results showed that the treatment of bleomycin, a DNA damaging agent, induced rat patellar TSC (PTSC) cellular senescence. The senescence was characterized by an increase in the senescence-associated β-galactosidase activity, as well as senescence-associated changes in cell morphology. On the other hand, rapamycin could extend lifespan in multiple species, including yeast, fruit flies, and mice, by decelerating DNA dam...
Source: Fight Aging! - Category: Research Authors: Tags: Newsletters Source Type: blogs
Conclusion: Use of 5-ASA was not associated with a lowered cancer risk in Chinese IBD patients. Addition of statin/aspirin provided no additional benefit.Key summaryInflammatory bowel diseases (IBD) including Crohn's disease and ulcerative colitis are associated with increased risk of both intestinal and extra- intestinal cancers.Various medications including 5-aminosalicylate acid (5-ASA), statins and aspirin have been studied for their chemoprevention effects. However, most studies focused on colorectal cancer only and showed conflicting evidence. No studies so far looked at the effects of these medications on all cancer...
Source: Scandinavian Journal of Gastroenterology - Category: Gastroenterology Tags: Scand J Gastroenterol Source Type: research
In this study, by adenovirus-mediated delivery and inducible transgenic mouse models, we demonstrate the proliferation of both HCs and SCs by combined Notch1 and Myc activation in in vitro and in vivo inner ear adult mouse models. These proliferating mature SCs and HCs maintain their respective identities. Moreover, when presented with HC induction signals, reprogrammed adult SCs transdifferentiate into HC-like cells both in vitro and in vivo. Finally, our data suggest that regenerated HC-like cells likely possess functional transduction channels and are able to form connections with adult auditory neurons. Epige...
Source: Fight Aging! - Category: Research Authors: Tags: Newsletters Source Type: blogs
Giuseppe Ristagno1*, Francesca Fumagalli1, Barbara Bottazzi2, Alberto Mantovani2,3,4, Davide Olivari1, Deborah Novelli1 and Roberto Latini1 1Department of Cardiovascular Research, Mario Negri Institute for Pharmacological Research IRCCS, Milan, Italy 2Humanitas Clinical and Research Center-IRCCS, Milan, Italy 3Humanitas University, Milan, Italy 4The William Harvey Research Institute, Queen Mary University of London, London, United Kingdom The long pentraxin PTX3 is a member of the pentraxin family produced locally by stromal and myeloid cells in response to proinflammatory signals and microbial moieties. The p...
Source: Frontiers in Immunology - Category: Allergy & Immunology Source Type: research
More News: Cholesterol | Inflammatory Bowel Disease | Nutrition | Statin Therapy | Ulcerative Colitis