History of infertility and risk of breast cancer: a prospective cohort study

To prospectively investigate the association between history of infertility and risk of breast cancer.
Source: Fertility and Sterility - Category: Reproduction Medicine Authors: Source Type: research

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J Clin Med. 2021 Sep 18;10(18):4235. doi: 10.3390/jcm10184235.ABSTRACT(1) Background: although most patients with epithelial ovarian cancer (EOC) undergo radical surgery, patients with early-stage disease, borderline ovarian tumor (BOT) or a non-epithelial tumor could be offered fertility-sparing surgery (FSS) depending on histologic subtypes and prognostic factors. (2) Methods: we conducted a systematic review to assess the safety and fertility outcomes of FSS in the treatment of ovarian cancer. We queried the MEDLINE, PubMed, Cochrane Library, and Cochrane ("Cochrane Reviews") databases for articles published i...
Source: Clinical Breast Cancer - Category: Cancer & Oncology Authors: Source Type: research
J Clin Med. 2021 Sep 16;10(18):4192. doi: 10.3390/jcm10184192.ABSTRACTA significant number of women receive a cancer diagnosis before their age of natural menopause. Among these patients, the most frequent neoplasms are breast cancer, gynecological, and hematological malignancies. Premature ovarian insufficiency and infertility are among the most feared short- to long-term consequences of anticancer treatments in premenopausal patients. Both patient- and treatment-related characteristics are key factors in influencing the risk of gonadotoxicity with the use of chemotherapy. The cryopreservation of oocytes/embryos is a stan...
Source: Clinical Breast Cancer - Category: Cancer & Oncology Authors: Source Type: research
J Clin Med. 2021 Sep 18;10(18):4235. doi: 10.3390/jcm10184235.ABSTRACT(1) Background: although most patients with epithelial ovarian cancer (EOC) undergo radical surgery, patients with early-stage disease, borderline ovarian tumor (BOT) or a non-epithelial tumor could be offered fertility-sparing surgery (FSS) depending on histologic subtypes and prognostic factors. (2) Methods: we conducted a systematic review to assess the safety and fertility outcomes of FSS in the treatment of ovarian cancer. We queried the MEDLINE, PubMed, Cochrane Library, and Cochrane ("Cochrane Reviews") databases for articles published i...
Source: Clinical Breast Cancer - Category: Cancer & Oncology Authors: Source Type: research
J Clin Med. 2021 Sep 16;10(18):4192. doi: 10.3390/jcm10184192.ABSTRACTA significant number of women receive a cancer diagnosis before their age of natural menopause. Among these patients, the most frequent neoplasms are breast cancer, gynecological, and hematological malignancies. Premature ovarian insufficiency and infertility are among the most feared short- to long-term consequences of anticancer treatments in premenopausal patients. Both patient- and treatment-related characteristics are key factors in influencing the risk of gonadotoxicity with the use of chemotherapy. The cryopreservation of oocytes/embryos is a stan...
Source: Clinical Breast Cancer - Category: Cancer & Oncology Authors: Source Type: research
ConclusionFP discussion rates are low and are influenced by patient and physician characteristics. There is therefore room for improvement in the promotion and systematization of FP discussion.
Source: Frontiers in Oncology - Category: Cancer & Oncology Source Type: research
Environ Sci Pollut Res Int. 2021 Sep 24. doi: 10.1007/s11356-021-16581-9. Online ahead of print.ABSTRACTUntainted environment promotes health, but the last few decades experienced steep upsurge in environmental contaminants posing detrimental physiological impact. The responsible factors mainly include the exponential growth of human population, havoc rise in industrialization, poorly planned urbanization, and slapdash environment management. Environmental degradation can increase the likelihood of human exposure to heavy metals, resulting in health consequences such as reproductive problems. As a result, research into met...
Source: Environmental Science and Pollution Research International - Category: Environmental Health Authors: Source Type: research
CONCLUSION: Screening mammography in women 40-49 performed prior to initiation of ART may identify asymptomatic breast malignancy. In accordance with ACR and SBI guidelines to screen women of this age group, women of this age group should undergo screening mammography prior to ART.PMID:34507268 | DOI:10.1016/j.clinimag.2021.08.028
Source: Clinical Genitourinary Cancer - Category: Cancer & Oncology Authors: Source Type: research
AbstractStudy questionDo different types of cancer affect the success of oocyte maturation in vitro compared to infertile women included in the in vitro fertilization (IVF) program?Summary answerCancer does not adversely affect oocyte maturation in vitro, with the exception of breast cancer, compared to infertile women in the in vitro fertilization program.What is known alreadyVitrification and storage of oocytes in liquid nitrogen is one of the real options for maintaining reproductive function in cancer patients. Despite careful hormonal stimulation of the ovaries, however, the proportion of oocytes is immature and lost ...
Source: Human Reproduction - Category: Reproduction Medicine Source Type: research
AbstractStudy questionIs unexplained recurrent pregnancy loss (RPL) related to long term cancer morbidity?Summary answerRecurrent unexplained pregnancy loss patients showed lower cancer morbidity. This trend was significant in the secondary aborters and in a sub-analysis for gynecological cancers.What is known alreadyThe association between infertility and cancer was studied, but has scarcely been studied in RPL; One study reported a higher incidence of breast and uterine cancers, while another found no association. Immune dysfunction is a possible cause of ‘unexplained RPL’; RPL patients have an increased numb...
Source: Human Reproduction - Category: Reproduction Medicine Source Type: research
THURSDAY, July 1, 2021 -- Women treated with ovarian stimulation drugs for infertility do not have a significantly increased risk of breast cancer, according to a systematic review and meta-analysis published in the July issue of Fertility and...
Source: Drugs.com - Pharma News - Category: Pharmaceuticals Source Type: news
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