Experimental animal models for moyamoya disease and treatment: a pathogenesis-oriented scoping review

CONCLUSIONS: Models generated for MMD have involved three general approaches: surgical, immunological, and genetic. Although each reflects a key aspect of MMD pathogenesis, the failure of any individual model to recapitulate the development, progression, and consequences of the disease underscores the importance of future work in developing a multietiology model.PMID:34469865 | DOI:10.3171/2021.6.FOCUS21284

Source: Neurosurgical Focus - September 1, 2021 Category: Neurosurgery Authors: Michael S Rallo Omar Akel Akhilesh Gurram Hai Sun Source Type: research