Heparin induced thrombocytopenia in relation to SARS-CoV-2 infection and ABO blood group

Since late 2020, a rare prothrombotic thrombocytopenic condition has been observed to arise within 5 to 30  days after vaccination against severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) [1]. This condition – called “Vaccine Induced Immune Thrombotic Thrombocytopenia” (VITT) – has many similarities to an atypical variant of heparin-induced thrombocytopenia, including unusual sites for VTE, in addition to positive platelet-activating antibodies against platelet factor 4 (PF4) [2]. Prior to SARS-CoV-2, “spontaneous HIT” was described in the absence of proximate exposure to heparin [3].
Source: Thrombosis Research - Category: Hematology Authors: Tags: Letter to the Editors-in-Chief Source Type: research