Management of Seizures in Neonates with Neonatal Encephalopathy Treated with Hypothermia

Neonatal encephalopathy (NE) is the most common etiology of acute neonatal seizures – about half of neonates treated with therapeutic hypothermia for NE have EEG-confirmed seizures. These seizures are best identified with continuous EEG monitoring, as clinical diagnosis leads to under-diagnosis of subclinical seizures and over-treatment of events that are not seizures. High seizu re burden, especially status epilepticus, is thought to augment brain injury. Treatment, therefore, is aimed at minimizing seizure burden.

Source: Seminars in Fetal and Neonatal Medicine - September 15, 2021 Category: Perinatology & Neonatology Authors: Oscar DeLaGarza-Pineda, Janette A. Mailo, Geraldine Boylan, Vann Chau, Hannah C. Glass, Amit M. Mathur, Renee Shellhaas, Janet S. Soul, Courtney J. Wusthoff, Taeun Chang, Newborn Brain Society Guidelines and Publications Committee Source Type: research