FOXO3a inhibits nephroblastoma cell proliferation, migration and invasion, and induces apoptosis through downregulating the Wnt/ β‑catenin signaling pathway

In conclusion, the findings of the present study suggested that FOXO3a may inhibit nephroblastoma cell proliferation, migration and invasion, while inducing apoptosis, by downregulating the Wnt/β‑catenin signaling pathway. These results may provide a novel method for the early diagnosis and precise treatment of nephroblastoma.PMID:34515328 | DOI:10.3892/mmr.2021.12436
Source: Molecular Medicine Reports - Category: Molecular Biology Authors: Source Type: research