Chronic inflammation-induced senescence impairs immunomodulatory properties of synovial fluid mesenchymal stem cells in rheumatoid arthritis

CONCLUSION: We conclude that a chronic RA inflammatory milieu affects the MSC potential. Therefore, this work addresses the importance of understanding MSC characteristics during disease states prior to their application in patients.PMID:34521481 | DOI:10.1186/s13287-021-02453-z

Source: Cell Research - September 15, 2021 Category: Cytology Authors: Hyeon-Jeong Lee Won-Jae Lee Sun-Chul Hwang Yongho Choe Saetbyul Kim Eunyeong Bok Sangyeob Lee Seung-Joon Kim Hyun-Ok Kim Sun-A Ock Hae-Sook Noh Gyu-Jin Rho Sang-Il Lee Sung-Lim Lee Source Type: research