Non-pharmacological Treatment for Children With Functional Constipation: A Systematic Review and Meta-analysis

To evaluate the effectiveness and safety of non-pharmacological interventions for the treatment of childhood functional constipation functional constipation.
Source: The Journal of Pediatrics - Category: Pediatrics Authors: Tags: Original Articles Source Type: research

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Chang Cassia obtusifolia L., of the Leguminosae family, is used as a diuretic, laxative, tonic, purgative, and natural remedy for treating headache, dizziness, constipation, tophobia, and lacrimation and for improving eyesight. It is commonly used in tea in Korea. Various anthraquinone derivatives make up its main chemical constituents: emodin, chrysophanol, physcion, obtusifolin, obtusin, au rantio-obtusin, chryso-obtusin, alaternin, questin, aloe-emodin, gluco-aurantio-obtusin, gluco-obtusifolin, naphthopyrone glycosides, toralactone-9-β-gentiobioside, toralactone gentiobioside, and cassiaside. C. obtusifolia&am...
Source: Molecules - Category: Chemistry Authors: Tags: Review Source Type: research
ConclusionMultiple perforations, severe peritonitis, and operation time more than 2  h are poor post-operative factors that were associated with poor post-operative outcome in our patients.
Source: Pediatric Surgery International - Category: Surgery Source Type: research
CONSTIPATION is a common problem, but most people don't realise that it can be fatal. Here are 10 reasons why and how to treat constipation.
Source: Daily Express - Health - Category: Consumer Health News Source Type: news
Am J Physiol Cell Physiol. 2021 Oct 13. doi: 10.1152/ajpcell.00334.2021. Online ahead of print.ABSTRACTChloride transport across cell membranes is broadly involved in epithelial fluid transport, cell volume and pH regulation, muscle contraction, membrane excitability, and organellar acidification. The human genome encodes at least 53 chloride transporting proteins with expression in cell plasma or intracellular membranes, which include chloride channels, exchangers and cotransporters, some having broad anion specificity. Loss of function mutations in chloride transporters cause a wide variety of human diseases, including c...
Source: American Journal of Physiology. Cell Physiology - Category: Cytology Authors: Source Type: research
CONCLUSIONS: Our study shows that a large proportion of children cannot adequately complete the QPGS-IV and that the intra-rater reliability among those who did adequately follow the instructions is moderate. We advise to test the children's understanding of the instructions prior to completion of questionnaires and recommend to not rely exclusively on a self-reported questionnaire to select, recruit, or evaluate pediatric patients for FGIDs for research purposes.PMID:34642283 | DOI:10.5056/jnm20179
Source: Journal of Neurogastroenterology and Motility - Category: Gastroenterology Authors: Source Type: research
J Neurogastroenterol Motil. 2021 Oct 30;27(4):602-611. doi: 10.5056/jnm20135.ABSTRACTBACKGROUND/AIMS: Chronic constipation and lifestyle factors can affect sleep quality. We evaluated the relationship between chronic constipation and sleep in the Japanese population.METHODS: This cross-sectional internet-based survey included 3000 subjects with constipation, classified according to sleep status (good/poor). Primary endpoints were Bristol stool form scale (BSFS) score and correlations between sleep disorder criteria of the Pittsburgh Sleep Quality Index (PSQI) and sleep status (good/poor sleep). Secondary endpoints included...
Source: Journal of Neurogastroenterology and Motility - Category: Gastroenterology Authors: Source Type: research
CONCLUSIONS: Eleven percent of patients with IBS self-reported wheat sensitivity. None of them had positive celiac serology; 60.9% were positive for HLA DQ2 and DQ8, suggesting a possible genetic basis. All of them improved symptomatically on a wheat-free diet.PMID:34642280 | DOI:10.5056/jnm20086
Source: Journal of Neurogastroenterology and Motility - Category: Gastroenterology Authors: Source Type: research
This study aims to elucidate clinical features associated with various types of EMDs in patients with heartburn symptoms.METHODS: Of the 511 patients who underwent high-resolution manometry, 394 who were evaluated for heartburn symptoms were examined. Patients subjected to high-resolution manometry were classified into 4 groups: outflow obstruction group, hypermotility group, hypomotility group, and normal motility group. Symptoms were evaluated using 3 questionnaires. Patient characteristics and symptoms for each EMD type were compared with those of the normal motility group.RESULTS: Of the 394 patients, 193 (48.9%) were ...
Source: Journal of Neurogastroenterology and Motility - Category: Gastroenterology Authors: Source Type: research
CONCLUSIONS: Bulk laxative, osmotic laxative, stimulant laxative with or without fiber, and other medications can be used in elderly patients in short-term within 3 months with reasonable safety. However, the quality of included studies was not high and most of studies was conducted in a small number of patients. Among these laxatives, polyethylene glycol seems to be safe and effective in long-term use of about 6 months in elderly patients.PMID:34642269 | DOI:10.5056/jnm20210
Source: Journal of Neurogastroenterology and Motility - Category: Gastroenterology Authors: Source Type: research
Am J Physiol Cell Physiol. 2021 Oct 13. doi: 10.1152/ajpcell.00334.2021. Online ahead of print.ABSTRACTChloride transport across cell membranes is broadly involved in epithelial fluid transport, cell volume and pH regulation, muscle contraction, membrane excitability, and organellar acidification. The human genome encodes at least 53 chloride transporting proteins with expression in cell plasma or intracellular membranes, which include chloride channels, exchangers and cotransporters, some having broad anion specificity. Loss of function mutations in chloride transporters cause a wide variety of human diseases, including c...
Source: Am J Physiol Cell Ph... - Category: Cytology Authors: Source Type: research
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