Risk Factors and Outcomes for Gastroparesis After Lung Transplantation
ConclusionWhile gastroparesis is common after lung transplantation, it remains difficult to predict which patients will develop these complications post-transplant. Black patients were more likely to be diagnosed with gastroparesis after adjusting for relevant confounders. Gastroparesis is associated with increased risk of CLAD, and further studies are needed to assess whether early detection and treatment can reduce the incidence of CLAD.
Conclusion: Secondary BS is safe, although postoperative morbidity exceeds the established benchmarks for primary BS. The excess morbidity is due to an increased risk of gastrointestinal leakage and higher need for intensive care. The considerable rate of tertiary BS warrants expertise and future research to optimize the management of non-success after BS.
Pediatric obesity is a chronic disease which leads to the development of significant health consequences in childhood, and increased risk of morbidity and premature mortality in adulthood. It is now estimated that 4% of children and 9% of adolescents in the United States have severe obesity (BMI ≥ 120% of the 95th percentile for age). (1) Causal factors for obesity include genetics, environment, medications, and behavior.(2) Severe obesity during childhood and adolescence is associated with the development of significant comorbidities such as cardiovascular disease, type 2 diabetes (T2D), obstructive sleep apnea (OSA), ...
Obesity is associated with increased intra-abdominal pressure, impaired gastric emptying, and decreased lower esophageal sphincter (LES) pressure, all factors predisposing for gastroesophageal reflux disease (GERD).1 Furthermore, autonomic neuropathy in diabetes may increase the risk of GERD because of abnormal peristalsis and reduced LES pressure. Accordingly, patients with obesity and/or type 2 diabetes have a high prevalence of GERD and esophageal motility disorders. Weight loss reduces acid reflux.
Background Around 8–10% of individuals over 50 years of age present interstitial lung abnormalities (ILAs), but their risk factors are uncertain. Methods From 817 individuals recruited in our lung ageing programme at the Mexican National Institute of Respiratory Diseases, 80 (9.7%) showed ILAs and were compared with 564 individuals of the same cohort with normal high-resolution computed tomography to evaluate demographic and functional differences, and with 80 individuals randomly selected from the same cohort for biomarkers. We evaluated MUC5B variant rs35705950, telomere length, and serum levels of matrix met...
Condition: Gastroesophageal Reflux Interventions: Other: Cognitive Behavioral Therapy; Other: Sham-SOC Lifestyle Coaching Sponsors: Northwestern University; National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK); Washington University School of Medicine; University of California, San Diego; Vanderbilt University School of Medicine Not yet recruiting
CONCLUSION: Bariatric surgery is feasible in patients with SSO. Revision procedures may increase risk of operative complications.PMID:34248332 | PMC:PMC8241285 | DOI:10.4293/JSLS.2020.00089