Megestrol acetate is a specific inducer of CYP3A4 mediated by human pregnane X receptor
ConclusionThe results suggest that megestrol acetate is a specific inducer of CYP3A4 mediated by hPXR and therefore has the potential to cause drug interactions, especially in the co-administration with drugs that are substrates of CYP3A4.
Source: Cancer Chemotherapy and Pharmacology - Category: Cancer & Oncology Source Type: research
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