The Negative Impacts of Acromegaly on Bone Microstructure Not Fully Reversible

ConclusionAcromegaly adversely affected bone quality, even in controlled patients. As the deterioration in bone microstructure due to prolonged GH/IGF-1 exposure was not fully reversible, clinicians should be aware of the bone fragility of acromegaly patients even after they had achieved biochemical remission.
Source: Frontiers in Endocrinology - Category: Endocrinology Source Type: research