Transcriptomic Repositioning Analysis Identifies mTOR Inhibitor as Potential Therapy for Epidermolysis Bullosa Simplex
Expression-based systematic drug repositioning has been explored to predict novel treatments for a number of skin disorders. Here, we utilize this approach to identify, to our knowledge, previously unreported therapies for epidermolysis bullosa simplex (EBS). RNA sequencing analysis was performed on skin biopsies of acute blisters (
Source: Journal of Investigative Dermatology - Category: Dermatology Authors: Gun Ho Lee, Ramrada Lekwuttikarn, Elidia Tafoya, Monica Martin, Kavita Y. Sarin, Joyce M. Teng Tags: Original Article Source Type: research