Reassessing the Role for Sympathetic Neurolysis in Patients with Pancreatic Cancer

“…what is the best role for sympathetic neurolysis in the management of pain associated with pancreatic cancer…?”
Source: Anesthesiology - Category: Anesthesiology Source Type: research

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With the new equipment and facility, New Mexico Cancer Center will ensure the company can offer both types of radiation used for cancer treatment.
Source: bizjournals.com Health Care:Biotechnology headlines - Category: Biotechnology Authors: Source Type: news
Dalton Trans., 2021, Advance Article DOI: 10.1039/D1DT02023D, PaperAhmet T. Bilgi çli, Ceylan Hepokur, Hayriye Genc Bilgicli, Burak Tüzün, Armağan Günsel, Sema Mısır, Mustafa Zengin, M. Nilüfer Yarasir α-substituted phthalocyanines were synthesized due to their promising anticancer compounds. Their aggregation behavior and biological properties were investigated by UV-Vis and fluorescence spectroscopy, as well as molecular docking studies. To cite this article before page numbers are assigned, use the DOI form of citation above. The content of this RSS Feed (c) The Royal Society of Chemistry
Source: RSC - Dalton Trans. latest articles - Category: Chemistry Authors: Source Type: research
Hello, I am a non-traditional student and I am looking to make a career change. The careers that I am interested in are dentistry and anesthesiologist assistant. I have shadowed and done my research on both professions and I love them both which is why I am having a difficult time making a decision. The prerequisites for dental and AA school are identical as well as the earning potential unless the dentist is a specialist or private practice owner. I don’t have any debt and I am currently... Read more
Source: Student Doctor Network - Category: Universities & Medical Training Authors: Tags: Pre-Dental Source Type: forums
Many companies give back for Breast Cancer Awareness Month, but consumers should make sure the money is going where it should.
Source: WebMD Health - Category: Consumer Health News Source Type: news
This study aimed to analyze the clinical safety and effectiveness of endoscopic ultrasound-guided celiac plexus neurolysis (EUS-CPN) in alleviating intractable abdominal pain caused by advanced pancreatic cancer. A total of 58 patients with inoperable pancreatic cancer who underwent EUS-CPN from May 2015 to December 2017 were enrolled. Pain levels before and after EUS-CPN were assessed and compared using the Visual Analogue Scale. The preoperative Visual Analogue Scale score was 8.2±2.3, which decreased significantly to 3.6±1.5 at 2 days after EUS-CPN and to 2.2±0.8 after 1 month. The response rate was...
Source: Surgical Laparoscopy, Endoscopy and Percutaneous Techniques - Category: Surgery Tags: Original Articles Source Type: research
By HANS DUVEFELT, MD A lot of Americans think they should be able to make an appointment with a specialist on their own, and view the referral from a primary care provider as an unnecessary roadblock. This “system” often doesn’t work, because of the way medical specialties are divided up. If belly pain is due to gallbladder problems you need a general surgeon. If it’s due to pancreas cancer, you need an oncologic surgeon. If the cause is Crohn’s disease, any gastroenterologist will do, but with Sphincter of Oddi problems, you’ll need a gastroenterologist who does ERCPs, and not ...
Source: The Health Care Blog - Category: Consumer Health News Authors: Tags: Medical Practice Physicians Hans Duvefelt primary care Source Type: blogs
Reena Goswami1, Gayatri Subramanian2, Liliya Silayeva1, Isabelle Newkirk1, Deborah Doctor1, Karan Chawla2, Saurabh Chattopadhyay2, Dhyan Chandra3, Nageswararao Chilukuri1 and Venkaiah Betapudi1,4* 1Neuroscience Branch, Research Division, United States Army Medical Research Institute of Chemical Defense, Aberdeen, MD, United States 2Department of Medical Microbiology and Immunology, University of Toledo College of Medicine and Life Sciences, Toledo, OH, United States 3Roswell Park Comprehensive Cancer Center, Buffalo, NY, United States 4Department of Physiology and Biophysics, Case Western Reserve University, Clev...
Source: Frontiers in Oncology - Category: Cancer & Oncology Source Type: research
Conclusion The expression of the components of the PTN-MK-RPTPβ/ζ axis in immune cells and in inflammatory diseases suggests important roles for this axis in inflammation. Pleiotrophin has been recently identified as a limiting factor of metainflammation, a chronic pathological state that contributes to neuroinflammation and neurodegeneration. Pleiotrophin also seems to potentiate acute neuroinflammation independently of the inflammatory stimulus while MK seems to play different -even opposite- roles in acute neuroinflammation depending on the stimulus. Which are the functions of MK and PTN in chronic neuroinfla...
Source: Frontiers in Pharmacology - Category: Drugs & Pharmacology Source Type: research
Gene-edited human embryo. Self-driving trucks. Practical quantum computers. 2017 has been an exciting year for science, technology – and digital health! It’s that time of the year again when it’s worth looking back at the past months; and list the inventions, methods and milestone events in healthcare to get a clearer picture what will shape medicine for the years to come. 2017 – Amazing year for science and healthcare Scientists, researchers, and innovators come up with amazing breakthroughs every year, and that was no different in 2017 either. No matter whether we look at physics (proving the exis...
Source: The Medical Futurist - Category: Information Technology Authors: Tags: Future of Medicine 3d printing artificial intelligence digital health genetics genomics Healthcare Innovation Personalized medicine robotics technology wearables Source Type: blogs
This study investigated the role of trypsin-protease activated receptor-2 (PAR-2) in pancreatic cancer pain. Pancreatic tissue samples were collected from pancreatic cancer (n=22) and control patients (n=22). Immunofluorescence analyses confirmed colocalization of PAR-2 and neuronal markers in pancreatic cancer tissues. Trypsin levels and protease activities were higher in pancreatic cancer tissue specimens than in the controls. Supernatants from cultured human pancreatic cancer tissues (PC supernatants) induced substance P and calcitonin gene-related peptide release in dorsal root ganglia (DRG) neurons, and FS-NH2, a sele...
Source: Oncotarget - Category: Cancer & Oncology Tags: Oncotarget Source Type: research
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