High-Intensity Statins Benefit High-Risk Patients: Why and How to Do Better

Review of the US and European literature indicates that most patients at high risk for atherosclerotic cardiovascular disease (ASCVD are not treated with high-intensity statins, despite strong clinical-trial evidence of maximal statin benefit. High-intensity statins are recommended for 2 categories of patients: those with ASCVD (secondary prevention) and high-risk patients without clinical ASCVD. Most patients with ASCVD are candidates for high-intensity statins, with a goal for low-density lipoprotein cholesterol reduction of 50% or greater.

Source: Mayo Clinic Proceedings - September 14, 2021 Category: Internal Medicine Authors: Scott M. Grundy, Neil J. Stone, Roger S. Blumenthal, Lynne T. Braun, Paul A. Heidenreich, Donald Lloyd-Jones, Carl E. Orringer, Joseph J. Saseen, Sidney C. Smith, Laurence S. Sperling, Salim S. Virani Tags: Consensus recommendation Source Type: research