Serum anti-M üllerian hormone as a marker of ovarian reserve after cancer treatment and/or hematopoietic stem cell transplantation in childhood: proposal for a systematic approach to gonadal assessment

Conclusions In non-transplanted patients, CED ≥ 7200 mg/m2 was associated with a DOR, while younger age at diagnosis played a protective role on ovarian reserve. As a result of the data collected, we propose a systematic algorithm to assess iatrogenic gonadal impairment in young female patients exposed to chemo-radiotherapy in childhood for hematological disorders.PMID:34519276 | DOI:10.1530/EJE-21-0351

Source: European Journal of Endocrinology - September 14, 2021 Category: Endocrinology Authors: Silvia Molinari Francesca Parissone Veronica Evasi Paola De Lorenzo Maria Grazia Valsecchi Simone Cesaro Donatella Fraschini Roberta Sangalli Gianluca Cacace Andrea Biondi Adriana Balduzzi Alessandro Cattoni Source Type: research