Allergic contact dermatitis caused by dipropylene glycol diacrylate in the Omnipod ® insulin pump
CONCLUSIONS: When suspecting ACD to MDs DPGDA at 0.1% in pet. should be tested. The content of Omnipod® has changed over time. Patch testing with updated test series and relevance assessment of positive reactions is a delicate task. Children, with lifelong use of MDs, risk contracting many allergies with potential cross-allergies. A question should be raised - whether these low molecular weight acrylates should at all be used in devices constantly worn on the skin.PMID:34510410 | DOI:10.1111/bjd.20751
Funding Opportunity RFA-AI-21-060 from the NIH Guide for Grants and Contracts. The purpose of the SUNBEAM - Analysis and Bioinformatics Center (SUNBEAM-ABC) is to establish a mechanistic omics center to support the birth cohort study Systems Biology of Early Atopy (SUNBEAM). The center will assay biologic samples collected within the SUNBEAM cohort using omics and systems biology approaches to identify determinants of atopic disease, focusing on food allergy and atopic dermatitis (AD) in newborns, infants, and very young children. SUNBEAM-ABC will support the SUNBEAM birth cohort study by providing analytic infrastructure...
Ann Allergy Asthma Immunol. 2021 Sep 16:S1081-1206(21)01028-0. doi: 10.1016/j.anai.2021.09.003. Online ahead of print.NO ABSTRACTPMID:34537359 | DOI:10.1016/j.anai.2021.09.003
CONCLUSION: AD patients have a higher incidence of fractures. Severe AD is independently associated with fractures.PMID:34537357 | DOI:10.1016/j.anai.2021.09.004
Conclusions and Clinical RelevanceCRE-DR is a mAb cross-reactive to dog and human IgEs, which can allow the use of a dog model of allergy to test the efficacy of a CRE-DR-derived anti-IgE therapeutic mAb before human clinical trials.
For this installment of ‘From the Pages of Allergy Watch’ I've selected articles from the July-Aug issue. The first, reviewed by Dr Lee, suggests that pretreatment with H1&H2 antihistamines and montelukast can reduce the risk for reaction to COVID-19 vaccination. The next, reviewed by Dr Hernandez-Trujillo, reports data suggesting that alpha-gal allergy can be a problem even in areas not endemic for the lone star tick. The last article, reviewed by Dr Joshi, presented data suggesting that children with more severe atopic dermatitis are more likely to have learning disabilities.
Increased attention towards infection control measures during the COVID-19 pandemic have brought to light the dermatological consequences of intensified hand hygiene measures. Healthcare workers are inherently at an increased risk of developing both allergic and irritant contact dermatitis. Individuals with a history of atopy are especially vulnerable given their impaired native skin barriers and increased sensitivities at baseline. Examination gloves not only induce contact allergies from manufacturing chemicals, but also serve as an occlusive catalyst for facilitating contact sensitization and irritant dermatitis. Simila...
The risk of osteoporosis has been explored in atopic dermatitis (AD). The long-term risk of fractures in AD patients and the effects of various AD treatment on bone health remain to be elucidated.
CONCLUSIONS: This review of 84 products found that tattoo aftercare products contain an average of 8 ACDS Core and 7 NACDG allergens. Clinicians should be aware of potential allergens in tattoo aftercare products.PMID:34524774 | DOI:10.1097/DER.0000000000000635
The estimated prevalence of atopic dermatitis (AD) in esophageal esophagitis (EoE) ranges from 2 –19%.1 We hypothesized that the presence of AD is associated with increased severity of EoE, defined as an increased rate of food impaction, esophageal stricture, or subepithelial fibrosis on biopsy in a cohort of pediatric patients. We further hypothesized that eosinophil counts on endoscopy woul d be higher in patients with EoE and concomitant AD, than in those without AD.
Vet Dermatol. 2021 Sep 14. doi: 10.1111/vde.13022. Online ahead of print.ABSTRACTBACKGROUND: The pathogenesis of feline allergic dermatitis (FAD) is unclear, with several differences from allergic dermatitis in dogs and humans.HYPOTHESIS/OBJECTIVES: To survey cytokine expression levels in healthy cats and cats affected with allergic dermatitis or asthma.ANIMALS: Formalin-fixed, paraffin-embedded skin biopsies from 22 cats with allergic dermatitis and 21 cats without allergic dermatitis were used for cutaneous assays. Serum was obtained from 17 healthy cats, 18 cats with allergic dermatitis, and 18 cats with a presumptive d...