Pyrroline-5-Carboxylate Reductase-2 Promotes Colorectal Cancer Progression via Activating PI3K/AKT/mTOR Pathway

CONCLUSION: PYCR2 was highly expressed in CRC, and its knockdown suppressed CRC tumorigenesis via inhibiting the activation of PI3K/AKT/mTOR pathway. This finding provides a new theoretical foundation for the treatment of CRC.PMID:34512817 | PMC:PMC8429024 | DOI:10.1155/2021/9950663

Source: Disease Markers - September 13, 2021 Category: Laboratory Medicine Authors: Feng Yin Xiaoxia Huang Yi Xuan Source Type: research