Evidence for marked underutilization of insurance billing in malignant pleural mesothelioma in Finland

Malignant pleural mesothelioma is a rare cancer, but one of the most frequent occupational malignant diseases. We evaluated the annual health care costs and changes in costs in Finland 2002 –2012. Compared with the average health care costs, the total costs and the cost per patient were growing 2-fold faster in mesothelioma patients. Only a proportion of healthcare costs were charged appropriately Workers' Compensation Insurance. AbstractBackgroundSubstantial variation in health care costs for malignant pleural mesothelioma (MPM) has previously been identified.Materials and MethodsWe analyzed the changes in health care costs in MPM in Finland during 2002 –2012. Finland has low-threshold public health care and a mandatory Workers' Compensation scheme that covers all occupational-related disease expenses. The costs include treatment costs for inpatients, hospice care, medication costs, rehabilitation costs, and travel costs. All costs are expressed in 2012 prices, adjusted using the consumer price index.ResultsA total of 907 MPM patients were included in the study. Mean duration of inpatient episodes increased 7% per year from 2002 to 2012, correlating with total costs (R2 = 0.861,p 
Source: Thoracic Cancer - Category: Cancer & Oncology Authors: Tags: ORIGINAL ARTICLE Source Type: research

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As expected, Johnson &Johnson has unloaded its burgeoning talc-related liabilities on a new subsidiary that filed for Chapter 11 bankruptcy protection on Oct. 14. The controversial move, which confirmed the fears of many personal injury attorneys, is an attempt by J&J to more easily resolve the thousands of current and future lawsuits claiming that its talc products have caused serious medical problems, including ovarian and mesothelioma cancers. Most of the claims contend that talc in the products was contaminated with toxic asbestos fibers. The filing, in U.S. Bankruptcy Court in the Western District of Nort...
Source: Asbestos and Mesothelioma News - Category: Environmental Health Authors: Source Type: news
Secondary exposure to toxic asbestos has declined dramatically in recent decades, but known cases of malignant mesothelioma caused by that type of asbestos exposure have continued to climb. Increasing awareness of the rare cancer has led to the contrasting trends and an expected rise in personal injury lawsuits involving secondary asbestos exposure. “One of the reasons is that we are getting better at diagnosing the disease,” attorney Daniel Wasserberg, who specializes in asbestos litigation, told The Mesothelioma Center at asbestos.com. “Years ago, a woman with classic mesothelioma symptoms, but wi...
Source: Asbestos and Mesothelioma News - Category: Environmental Health Authors: Source Type: news
Bull Cancer. 2021 Oct 12:S0007-4551(21)00374-X. doi: 10.1016/j.bulcan.2021.07.010. Online ahead of print.NO ABSTRACTPMID:34654542 | DOI:10.1016/j.bulcan.2021.07.010
Source: Bulletin du Cancer - Category: Cancer & Oncology Authors: Source Type: research
ConclusionThe present study showed that sarcomatoid carcinoma had a higher PD-L1 expression compared to non-small-cell lung cancer and that both PSC and MPM tended to exhibit PD-L1 positivity in the sarcomatoid compartment. Moreover, while immune checkpoint inhibitors may somewhat prolong the prognosis of both tumors, further studies with a larger cohort are necessary to confirm our results.
Source: Thoracic Cancer - Category: Cancer & Oncology Authors: Tags: ORIGINAL ARTICLE Source Type: research
NEW BRUNSWICK, N.J., October 14, 2021 – Johnson &Johnson (NYSE: JNJ) (the Company) today announced that LTL Management LLC (LTL), a newly created and separate subsidiary of Johnson &Johnson, that was established to hold and manage claims in the cosmetic talc litigation, has filed for voluntary Chapter 11 bankruptcy protection. This filing is intended to resolve all claims related to cosmetic talc in a manner that is equitable to all parties, including any current and future claimants. Johnson &Johnson and its other affiliates did not file for bankruptcy protection and will continue to operate their busine...
Source: Johnson and Johnson - Category: Pharmaceuticals Tags: Latest News Source Type: news
Facing legal pressure from health and advocacy organizations, the U.S. Environmental Protection Agency has agreed to broaden its ongoing Risk Evaluation for Asbestos under the Toxic Substances Control Act. An agreement to settle two lawsuits – both alleging inadequate evaluation of toxic asbestos – was filed Oct. 13 in the U.S. Court of Appeals for the Ninth Circuit in San Francisco. The Asbestos Disease Awareness Organization was the lead plaintiff in the risk evaluation litigation and was joined by health organizations, scientists and doctors, including acclaimed thoracic surgeon Dr. Raja Flores of Moun...
Source: Asbestos and Mesothelioma News - Category: Environmental Health Authors: Source Type: news
Memorial Sloan Kettering Cancer Center in New York City has opened a novel clinical trial that combines the immunotherapy drug Keytruda with cryoablation for patients with unresectable malignant mesothelioma. The phase I trial opened in September and will be available at seven Memorial Sloan Kettering locations in the New York City/New Jersey area. Cryoablation, which is also known as cryotherapy or cryosurgery, is a treatment that freezes localized tumors with argon gas or liquid nitrogen. It has been used effectively with liver, kidney and prostate cancers, but its use with mesothelioma has been limited because of ...
Source: Asbestos and Mesothelioma News - Category: Environmental Health Authors: Source Type: news
Fridlender Neutrophils play a key role in cancer biology. In contrast to circulating normal-density neutrophils (NDN), the amount of low-density neutrophils (LDN) significantly increases with tumor progression. The correlation between these neutrophil subpopulations and intratumoral neutrophils (TANs) is still under debate. Using 4T1 (breast) and AB12 (mesothelioma) tumor models, we aimed to elucidate the source of TANs and to assess the mechanisms driving neutrophils’ plasticity in cancer. Both NDN and LDN were found to migrate in response to CXCL1 and CXCL2 exposure, and co-infiltrate the tumor site ex vivo an...
Source: Cancers - Category: Cancer & Oncology Authors: Tags: Article Source Type: research
Thin-tissue tumors like mesothelioma are hard to treat, but a new injectable or sprayable hydrogel could change that
Source: Chemical and Engineering News - Category: Chemistry Authors: Source Type: research
Conditions:   Pancreatic Adenocarcinoma;   Hepatocellular Carcinoma;   Squamous Cell Carcinoma;   Mesothelioma;   Non-squamous Non-small-cell Lung Cancer;   Triple Negative Breast Cancer;   Gastroesophageal Junction Adenocarcinoma;   Esophageal Adenocarcinoma;   Gastric Adenocarcinoma Interventions:   Drug: TAK-500;   Drug: Pembrolizumab Sponsor:   Takeda Not yet recruiting
Source: ClinicalTrials.gov - Category: Research Source Type: clinical trials
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