Distinct genetic landscape and a low response to doxorubicin in a luminal-A breast cancer cell line of Pakistani origin

CONCLUSION: This study presents a distinct genetic architecture in luminal-A breast cancer potentially responsible for differential response to chemotherapy. Further studies on large cohorts of breast cancer patients are suggested for implementation in personalized medicine.PMID:34495459 | DOI:10.1007/s11033-021-06681-7

Source: Mol Biol Cell - September 8, 2021 Category: Molecular Biology Authors: Muhammad Shakeel Salman Ahmed Khan Anum Jabeen Mughal Muhammad Irfan Daniel C Hoessli M Iqbal Choudhary Muhammad Aurongzeb Ishtiaq Ahmad Khan Source Type: research