Chronic Pharmacological Modulation of Mitochondrial Dynamics Alleviates Prediabetes-Induced Myocardial Ischemia –Reperfusion Injury by Preventing Mitochondrial Dysfunction and Programmed Apoptosis

ConclusionChronic inhibition of mitochondrial fission and promotion of fusion exerted cardioprevention in prediabetes with cardiac I/R injury through the relief of cardiac mitochondrial dysfunction and dynamic alterations, and reduction in myocardial infarction, thus improving cardiac function.
Source: Cardiovascular Drugs and Therapy - Category: Cardiology Source Type: research