A Comparison of Isotoxic Dose-escalated Radiotherapy in Lung Cancer with Moderate Deep Inspiration Breath Hold, Mid-ventilation and Internal Target Volume Techniques

CONCLUSION: mDIBH aids lung and heart dose sparing in isotoxic dose-escalated radiotherapy compared with four-dimensional planning techniques. Given concerns about lung and cardiac toxicity, particularly in an era of consolidation immunotherapy, reduced normal tissue doses may be advantageous for treatment tolerance and outcome.PMID:34503896 | DOI:10.1016/j.clon.2021.08.012

Source: Clinical Lung Cancer - September 10, 2021 Category: Cancer & Oncology Authors: H Bainbridge A Dunlop D McQuaid S Gulliford R Gunapala M Ahmed I Locke S Nill U Oelfke F McDonald Source Type: research